Mammalian cDNA
Genscript Corporation Fc gamma RIIA/CD32a R167Bio
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains these groups are designated Fc gamma RI (also known as CD64) Fc gamma RII (CD32) and Fc gamma RIII (CD16) Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type The CD64 proteins are high affinity receptors ( 10e-8-10e-9 M) capable of binding monomeric IgG whereas the CD16 and CD32 proteins bind IgG with lower affinities ( 10e-6-10e-7 M) only recognizing IgG aggregates surrounding multivalent antigens
ABclonal Technology GNAQ Rabbit pAb
This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.
